Prof. Premysl Jiruska (excellent researcher, RWP2 leader) is Head of the Department of Physiology at the Second Faculty of Medicine. He is internationally recognized for his research on the pathophysiology of epilepsy, the organization of epileptic networks, and pathological oscillations. He started his career as a pediatric neurologist interested in epilepsy and epilepsy surgery. After completing his Ph.D. studies, he worked as a postdoctoral research fellow in Prof John Jeffery’s group in the United Kingdom. In 2008 he was awarded a personal research fellowship from Epilepsy Research UK, a competitive and prestigious award for the most promising epilepsy researchers. Currently, his research group focuses on the mechanisms regulating seizure genesis within abnormally connected epileptic networks and on the network principles governing seizure dynamics in experimental models and humans. He has expertise in both in vitro and in vivo electrophysiological techniques, digital signal processing, and several experimental models of epilepsy. Prof. Jiruska is a Project Manager of the Epilepsy Research Centre Prague, which brings together scientists and clinicians who share an interest in epilepsy research.